Surgery Education - Our Residents & Fellows
Emmanuel Gabriel, MD
General Surgery Resident
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Education:
MD, University of Medicine and Dentistry, Robert Wood Johnson Medical School - Piscataway, New Jersey, 2009
PhD, University of Medicine and Dentistry, Robert Wood Johnson Medical School - Piscataway, New Jersey, 2007
Other Postgraduate Training:
2004-2007, UMDNJ - The Graduate School of Biomedical Sciences, Piscataway, NJ; and The Cancer Institute of New Jersey, New Brunswick, NJ.
Thesis: "Modulation of regulatory T cells overcomes systemic anergy to tumor-associated antigen and enhances the antitumor effects of recombinant vaccinia virus vaccines."
Thesis Advisor: Edmund C. Lattime, PhD
Research Experience: cancer immunology and immunotherapy
Publications:
Gabriel EM, Jatoi I.
Breast
cancer chemoprevention.
Expert Rev Anticancer Ther. 2012 Feb;12(2):223-8.
Gabriel EM, Campbell WC. Effect of ambient salinity on immobilization of Caenorhabditis elegans by nematocidal agents. Parasitology Research. Aug 2003;90(5):390-2.
Goydos JS, Mann B, Kim HJ, Gabriel EM, Alsina J, Germino FJ, Shih W, Gorski DH. The detection of B-RAF and N-RAS mutations in human melanoma. Journal of the American College of Surgeons. Mar 2005;200(3):362-70.
Gabriel EM and Lattime EC. Anti-CTL-associated antigen 4: are regulatory T cells a target? Clinical Cancer Research. Feb 2007;13(3):785-8.
Gabriel EM, Monken CE, Lattime EC. Modulation of regulatory T cells (Tregs) enhances the antitumor effects of MHC Class I and Class II dominant antigenic vaccines. In preparation.
Gabriel EM and Lattime EC. Identification of Tumor Antigen Specific Regulatory T Cells in Primary Tumor of a Mouse Model. In preparation.
Presentations:
2006, Tumor Vaccine and Cell Therapy (TVACT) Working Group - Oral
Presentation: "Systemic depletion of CD4+CD25+ regulatory T cells
(Tregs) enhances the therapeutic antitumor effects of a recombinant
vaccinia virus vaccine encoding tumor-specific MHC Class I and Class II
dominant epitopes and the GMCSF gene."
2006, American Association for Cancer Research (AACR) 97th Annual Meeting - Oral Presentation, "Systemic depletion of CD4+CD25+ regulatory T cells (Tregs) enhances the therapeutic antitumor effects of a recombinant vaccinia virus vaccine encoding tumor-specific MHC Class I and Class II dominant epitopes and the GMCSF gene."
2006, National MD/PhD Student 21st Annual Conference - Oral Presentation: Oral Presentation, "Systemic depletion of CD4+CD25+ regulatory T cells (Tregs) enhances the therapeutic antitumor effects of a recombinant vaccinia virus vaccine encoding tumor-specific MHC Class I and Class II dominant epitopes and the GMCSF gene."
2007, American Association for Cancer Research (AACR) Centennial Meeting - Minisymposium Oral Presentation: "Modulation of tumor antigen specific regulatory T cells in combination with systemic vaccination produces tumor regression."
2007, 48th Annual National Student Research Forum (NSRF) - Oral Presentation: "Blocking regulatory T cells (Tregs) overcomes systemic anergy to immunization with MHC Class I or Class II dominant antigenic vaccines."
2007, Annual Retreat on Cancer Research in New Jersey - Oral Presentation: "Effects of regulatory T cell blockade and vaccine immunotherapy on antitumor responses in a murine bladder cancer model." Abstract Award - Gallo Award for Excellence in Research
2002, 47th Annual Meeting of the New Jersey Academy of Science and Affiliated Societies - Poster: "Effects of salinity on the efficacy of selected anthelmintic agents."
2006, Annual Retreat on Cancer Research in New Jersey - Oral Presentation: "Systemic depletion of CD4+CD25+ regulatory T cells (Tregs) enhances the therapeutic antitumor effects of a recombinant vaccinia virus vaccine encoding tumor-specific MHC Class I and Class II dominant epitopes and the GMCSF gene." Abstract Award - Gallo Award for Excellence in Research: $50
2005, Annual Retreat on Cancer Research in New Jersey; Poster: "Immune regulatory mechanisms in the tumor-host interaction."
Professional organizations:
Research experience:
Research Experience: cancer immunology and immunotherapy
Honors and Awards:
2013, J. Bradley Aust Surgical Society Traveling Fellowship
2011, Arnold P. Gold Resident Humanism and Excellence in Teaching Award
2007, UMDNJ - Graduate School of Biomedical Sciences (GSBS) Student Travel Award
2006, New Jersey Commission on Cancer Research (NJCCR) Predoctoral Fellowship
2006, UMDNJ - Graduate School of Biomedical Sciences (GSBS) Student Travel Award
2003, UMDNJ - Robert Wood Johnson Medical School (RWJMS) Summer Research Fellowship
2002, Beta Beta Beta (National Biology Honor Society)
2001, Automatic Data Processing, Inc. Science Scholarship
2001, Phi Beta Kappa
2001, Omicron Delta Epsilon (National Economics Honor Society)
1998, Dean Recognition Scholarship, Drew University, 36 Madison Avenue, Madison, NJ.
1998, Edward J. Bloustein Distinguished Scholarship, New Jersey Higher Education
Student Assistance Authority, Trenton, NJ.
Biosketch: Dr. Emmanual Gabriel did his undergraduate work at Drew University in New Jersey with a double major in Biology and Economics. He then entered the MD/PhD Program at Robert Wood Johnson Medical School. Dr. Gabriel completed his PhD in Biomedical Sciences at The Cancer Institute of New Jersey with emphasis on cancer immunology and immunotherapy. He was awarded a predoctoral fellowship from the New Jersey Commission on Cancer Research, and his thesis has formed the basis for several national presentations and publications. Dr. Gabriel hopes to become a physician scientist in surgical oncology.
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